Key Ingredients in the Best Supplements for Weight Loss

When choosing a fat-burning supplement, make sure it includes ingredients backed by science to support weight loss in one or more ways.

Green Tea Extract

Green tea extract contains an antioxidant called EGCG, which helps burn fat by inhibiting enzymes like pancreatic lipase.

Studies have shown that drinking green tea daily may reduce your body weight and fat. It is especially reputed for being effective at helping women burn belly fat [1].

It’s no wonder it’s included in Trimtone, Instant Knockout Cut, and Transparent Labs Body Recomp!

Green Coffee Bean Extract

As one of the ingredients in Trimtone, green coffee bean extract comes from unroasted coffee beans and contains caffeine.

The green coffee bean speeds up the fat-burning process and slows down the digestion of carbohydrates. It may also have a beneficial effect on your blood pressure and blood glucose levels [2].

Caffeine

A part of several formulas in our list, caffeine is a stimulant that gives you an extra dose of energy. What’s more, it contributes to weight loss by boosting metabolism and suppressing appetite.

Research shows that caffeine may help reduce your weight, body fat, and BMI. Additional studies suggest that caffeine has a positive impact on energy expenditure and thermogenesis during physical activity [3] [4].

Glucomannan

Glucomannan, derived from the konjac plant, has grown popular since it helps suppress your appetite. Within the stomach, it absorbs water and forms an indigestible lining, making you feel fuller longer [5] [6].

You can find glucomannan in Trimtone, Instant Knockout Cut, and other top supplements for weight loss that females take to curb their hunger pangs.

Best Supplements for Weight Loss Female Users Love in 2025 Reviewed in Detail

Ready to kickstart your journey toward a healthier, slimmer you? Below, we’ve rounded up the 8 best weight loss supplements for women, each packed with ingredients designed to help burn fat, boost metabolism, and support your fitness goals.

1. PhenQ - Best Weight Loss Supplement for Females 

If you want a single product that offers the benefits of several best supplements for weight loss, female users like you might find PhenQ a convenient, potent solution. It assists you in shedding extra pounds by revving up your metabolism to torch fat, reducing your cravings, toning down your appetite, blocking new fat formation, and improving your mood.

Some of the ingredients in its powerful formula are nopal cactus, capsimax powder, l-carnitine, chromium picolinate, caffeine, and the patented α-Lacys Reset.

Take 2 capsules every day, 1 before breakfast and 1 before lunch.

A lot of users approve of PhenQ as a weight loss supplement. For instance, in r/askfitness, u/ethangibas21 tried it after seeing different folks recommend it as the best fat burner for women. While this Redditor said it practically does everything it promises for him, he is also curious to know what other people’s experiences are with the product [7].

>>Explore PhenQ’s all-purpose weight loss formula

2. Trimtone - Great for Appetite Control

Trimtone is our go-to choice among the best supplements for burning fat for ladies who wish to control their appetite. Created by Health Nutrition, it can help you get rid of those excess pounds by crushing your cravings and burning body fat.

It showcases natural ingredients, such as glucomannan, caffeine anhydrous, green coffee bean extract, green tea extract, and grains of paradise.

Take 1 capsule every morning around half an hour before breakfast.

Many customers appreciate the weight loss benefits of Trimtone. In r/betterconsumerreports, for example, u/SpiritedPen112 shared that this supplement helped her drop 28 pounds in 5 months, even as a busy mom. On the other hand, this Reddit reviewer also clarified that she still watches what she eats and tries to stay active to get good results [8].

>>Buy Trimtone from the official website

2. Capsiplex Trim - Best for Breaking Through Plateaus

Need help breaking through a plateau? Thanks to its multi-action formula, Capsiplex Trim could be one of the best supplements for weight loss during menopause or other periods when you’ve “hit the wall.”

It assists you in cutting fat while controlling your cravings, as well as fighting fatigue to motivate you to finish exercising. Aside from patented compounds like Innoslim and Capsimax, it also comes with chromium, caffeine, and some of the best women's vitamins for energy and weight loss (like B6, B9 or folic acid, C, and D).

On an empty stomach, take Capsiplex Trim half an hour before exercising or before breakfast. At present, the official website doesn’t say how many capsules to take per serving.

On Capsiplex Trim’s official site, a verified user named Yanet G. was happy that the supplement helped her drop 9 pounds and 1.5 inches from her waist after 6 weeks [9]. You may also ask your family and friends who’ve used the product for unbiased feedback.

>>Find out how Capsiplex Trim combats a weight loss plateau

3. KetoCharge - Good for Ketosis

Trying to follow the keto diet? KetoCharge might be one of the best supplements for weight loss for women like you.

It encourages your body to go into ketosis faster, where your body burns fat for energy instead of sugar. The simple formula features “slimming salts,” like magnesium, sodium, and calcium beta-hydroxybutyrate.

Take 2 capsules every morning as soon as you wake up.

On Trustpilot, Elizabeth Walker shared that KetoCharge aided in her digestion and made her feel more vibrant and energetic. Nonetheless, she called it a great “addition” to her keto diet, not a replacement [10].

>>Learn how KetoCharge kickstarts ketosis

4. Phen24 - Round-the-Clock Support

If you need support for your weight loss efforts 24/7, Phen24 could be one of the best supplements for weight loss that female users like yourself will appreciate, thanks to its dual formula.

Its day supplement comes with caffeine, guarana extract, and cayenne powder, while the night formula includes some of the best vitamins for weight loss in women (such as B1, B5 or pantothenic acid, B6, and C).

Pop 2 capsules during breakfast time, then take 4 capsules around 15 minutes before dinner.

In a Trustpilot review, Sharon Guidotti found the 24-hour formula unique. She noticed that it increased her energy levels, reduced her cravings, and improved sleep quality, although it took a few weeks before she saw results [11].

>>Try Phen24’s weight loss formula

Natural Alternatives to Weight Loss Pills

If you prefer a natural approach over weight loss medications, remember that weight loss supplements aren’t your only option. There are plenty of other natural strategies you can explore. Check out some effective alternatives below!

Herbal Teas

Having trouble swallowing pills? You can drink herbal teas instead to enjoy a warm, soothing cup while enjoying weight loss benefits.

For instance, dandelions may improve fat metabolism and regulate blood sugar levels [12]. What’s more, matcha could also help prevent obesity and fat accumulation [13].

Apple Cider Vinegar

It’s a good idea to use apple cider vinegar as a cooking ingredient, condiment or acv gummies After all, it could aid in lowering your weight, body mass index, body fat ratio, and waist and hip measurements. It may even help manage your blood sugar and cholesterol levels [14].

Probiotics for Gut Health

Several studies show that probiotics may reduce body weight and body mass index by playing a role in digestion [15]. You can either take probiotic products with digestive enzymes or eat foods that are rich in probiotics, such as yogurt, kimchi, pickles, or cheese.

Dietary Fiber

We already talked about how glucomannan can help delay your hunger [5] [6]. While it’s included in Trimtone and other top supplements, you can also consume it in food form, including konjac rice or noodles.

In addition to fiber supplements, other foods packed with fiber can also help you feel full, like whole grains, vegetables, fruits, seeds, and nuts.

Lifestyle Tips To Maximize Supplement Results

Follow these tips to lower your body weight and avoid weight gain.

Nutrition

What you eat and how much you eat can influence how much weight you’ll lose (or gain!). To drop pounds, you simply have to burn more calories than you consume.

There’s no need for any crash diets! A low-calorie diet usually involves eating between 1,000-1,500 calories per day, with deficits ranging from 500 to 750 calories a day [16].

Aside from watching your calorie count, eat a healthy diet with protein, vitamins, minerals, and amino acids that can keep you fit and strong.

Exercise

Combining strength and cardio workouts could be a smart exercise strategy. After all, aerobic activity may help you cut down your fat mass and body mass, while resistance training allows you to build more lean muscle mass [17].

Sleep and Stress Management

Getting enough sleep and managing your stress are part of a lifestyle that supports a healthy weight [18]. Do your best to sleep and wake up at regular times to develop stable sleeping habits. Additionally, try relaxation practices such as yoga, meditation, or pilates to fight stress.

Hydration and Consistency

Drinking lots of water makes it easier for you to shed pounds in two ways [19]:

Common Mistakes To Avoid

Even if you’re taking the best weight loss supplements, be sure to avoid making these rookie mistakes:

FAQs on Best Supplements for Weight Loss for Women

Curious to learn more about top weight loss supplements for women? Check out our Q-and-A section!

What Are the Best Supplements for Weight Loss in Women?

We picked Trimtone as the top supplement women looking to lose weight ought to consider. After all, it contains natural ingredients that support the weight loss goals of women. Nevertheless, all the supplements we reviewed have their perks.

Are There Weight Loss Supplements Specifically Formulated for Females?

Yes, some weight loss supplements are designed especially for women, such as Trimtone. These formulas take into account the particular fitness needs of ladies.

Do Fat Burners Work Differently for Women Than for Men?

Yes, fat burners work differently for men and women. After all, guys have more lean muscle mass and a higher basal metabolic rate that allows them to lose weight faster than ladies.

What Ingredients Should Women Look for in Weight Loss Supplements?

The best supplements for weight loss for females are those that include research-backed ingredients that may encourage fat-burning or curb the appetite, such as green tea extract, caffeine, and glucomannan [1] [3] [5]. Check if it contains the best vitamins for weight loss for females as well.

Are Natural Supplements Effective for Women’s Weight Loss?

It depends. While they’re not magic pills, supplements have the potential to support your weight loss efforts, such as lowering your calorie intake and working out consistently. Still, how effective a natural fat burner may vary with each person and other factors, such as your starting weight, metabolism, and lifestyle.

Conclusion on Women’s Weight Loss Supplements

Shedding those extra pounds isn’t easy, but the right weight loss supplements can make the journey a bit smoother. With natural ingredients, they can help curb cravings, boost your metabolism, and support fat loss.

Whether you’re considering PhenQ or another option from our list, remember that your pick of the best supplement for weight loss is a personal choice for every woman!

References

1. Huang, J., Wang, Y., Xie, Z., Zhou, Y., Zhang, Y., & Wan, X. (2014). “The anti-obesity effects of green tea in human intervention and basic molecular studies.” European Journal of Clinical Nutrition, 68(10), 1075–1087. https://pubmed.ncbi.nlm.nih.gov/25074392/
2. Haidari, F., Samadi, M., Mohammadshahi, M., Jalali, M.T. & Engali, K.A. (2017): ‘Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women’. Asia Pacific Journal of Clinical Nutrition, 2017; 26(6):1048-1054, https://pubmed.ncbi.nlm.nih.gov/28917230/
3. Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z; “The Effects of Caffeine Intake on Weight Loss: A Systematic Review and DOS-Response Meta-Analysis of Randomized Controlled Trials.” Critical Reviews in Food Science and Nutrition, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/30335479/
4. Clark, Kathryn S, et al. “Caffeine Enhances Activity Thermogenesis and Energy Expenditure in Rats.” Clinical and Experimental Pharmacology & Physiology, U.S. National Library of Medicine, May 2019, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467726/
5. “Scientific Opinion on the Substantiation of Health Claims Related to Konjac Mannan (Glucomannan) and Reduction of Body Weight (ID 854, 1556, 3725), Reduction of Post-Prandial Glycaemic Responses (ID 1559), Maintenance of Normal Blood Glucose Concentrations (ID 835, 3724), Maintenance of Normal (Fasting) Blood Concentrations of Triglycerides (ID 3217), Maintenance of Normal Blood Cholesterol Concentrations (ID 3100, 3217), Maintenance of Normal Bowel Function (ID 834, 1557, 3901) and Decreasing Potentially Pathogenic Gastro-Intestinal Microorganisms (ID 1558) Pursuant to Article 13(1) of Regulation (EC) No 1924/2006.” European Food Safety Authority, https://www.efsa.europa.eu/en/efsajournal/pub/1798
6. B;, Devaraj RD;Reddy CK;Xu. “Health-Promoting Effects of Konjac Glucomannan and Its Practical Applications: A Critical Review.” International Journal of Biological Macromolecules, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/30586587/
7. Reddit - The heart of the internet. (2024). Reddit.com. https://www.reddit.com/r/askfitness/comments/1fi9eac/best_fat_burners_for_women/
8. R/Betterconsumerreports on Reddit: Trimtone Review: How This Busy Mom Lost 28 Pounds in 5 Months, www.reddit.com/r/betterconsumerreports/comments/1fm4dff/trimtone_review_how_this_busy_mom_lost_28_pounds/.
9. Fat Burner For Women | Capsiplex Trim. (2022). Capsiplex (USA). https://capsiplex.com/pages/trim/
10. Elizabeth Walker gave Keto Charge 【Official & Deals ✔️✔️✔️ 】 5 stars. Check out the full review... (2024, March 27). Trustpilot; Trustpilot. https://www.trustpilot.com/reviews/660414e83a424323f545826a
11. Sharon Guidotti gave Phen24 Fat Burner Diet 5 stars. Check out the full review... (2025, January 30). Trustpilot. https://au.trustpilot.com/reviews/679b8e916a958a21e78faef5
12. Kania-Dobrowolska, M., & Baraniak, J. (2022). Dandelion (Taraxacum officinale L.) as a Source of Biologically Active Compounds Supporting the Therapy of Co-Existing Diseases in Metabolic Syndrome. Foods, 11(18), 2858. https://doi.org/10.3390/foods11182858
13. Wang, Y., Yu, Y., Ding, L., Xu, P., & Zhou, J. (2022). Matcha green tea targets the gut–liver axis to alleviate obesity and metabolic disorders induced by a high-fat diet. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.931060
14. Abou-Khalil, R., Andary, J., & El-Hayek, E. (2024). Apple cider vinegar for weight management in Lebanese adolescents and young adults with overweight and obesity: a randomised, double-blind, placebo-controlled study. BMJ Nutrition, Prevention & Health, e000823. https://doi.org/10.1136/bmjnph-2023-000823
15. Torres, B., Sánchez, M. C., Virto, L., Arancha Llama‐Palacios, Ciudad, M. J., & Collado, L. (2024). Use of probiotics in preventing and treating excess weight and obesity. A systematic review. Obesity Science & Practice, 10(3). https://doi.org/10.1002/osp4.759
16. Kim, J. Y. (2020). Optimal diet strategies for weight loss and weight loss maintenance. Journal of Obesity & Metabolic Syndrome, 30(1), 20–31. https://doi.org/10.7570/jomes20065
17. Willis, L. H., Slentz, C. A., Bateman, L. A., Shields, A. T., Piner, L. W., Bales, C. W., Houmard, J. A., & Kraus, W. E. (2012). Effects of aerobic and/or resistance training on body mass and fat mass in overweight or obese adults. Journal of Applied Physiology, 113(12), 1831–1837. https://doi.org/10.1152/japplphysiol.01370.2011
18. Centers for Disease Control and Prevention. (2024, February 26). Steps for Losing Weight. Healthy Weight and Growth. https://www.cdc.gov/healthy-weight-growth/losing-weight/index.html
19. ‌Thornton, S. N. (2016). Increased Hydration Can Be Associated with Weight Loss. Frontiers in Nutrition, 3(18). https://doi.org/10.3389/fnut.2016.00018